The 25 Most Downloaded Articles from
European Journal of Pharmacology

1. Neurobiology of overeating and obesity: The role of melanocortins and beyond • Review article
2. Metformin reduces cisplatin-mediated apoptotic death of cancer cells through AMPK-independent activation of Akt
3. Central effects of stress hormones in health and disease: Understanding the protective and damaging effects of stress and stress mediators • Review article
4. Epigenetics and cancer treatment • Review article
5. Health effects of quercetin: From antioxidant to nutraceutical • Review article
6. Recent advances in the study on capsaicinoids and capsinoids • Review article
7. Resveratrol, obesity and diabetes • Review article
8. Biochanin-A, an isoflavon, showed anti-proliferative and anti-inflammatory activities through the inhibition of iNOS expression, p38-MAPK and ATF-2 phosphorylation and blocking NF¿B nuclear translocation
9. The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review
10. Inhibition of cell survival, invasion, tumor growth and histone deacetylase activity by the dietary flavonoid luteolin in human epithelioid cancer cells
11. Inhibition of soluble epoxide hydrolase attenuates endothelial dysfunction in animal models of diabetes, obesity and hypertension
12. Effects of antidiabetic drugs in high-fat diet and streptozotocin-nicotinamide-induced type 2 diabetic mice
13. The flavonoid quercetin induces cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells through p53 induction and NF-¿B inhibition
14. Pharma-nutrition interface: The gap is narrowing • Review article
15. Pathobiology of neuropathic pain • Review article
16. Modulation of the central melanocortin system by leptin, insulin, and serotonin: Co-ordinated actions in a dispersed neuronal network • Review article
17. The mouse light/dark box test
18. Targeting the endoplasmic reticulum-stress response as an anticancer strategy • Review article
19. Reactive oxygen species and endothelial function in diabetes • Review article
20. Inhibition of DPP-4 with sitagliptin improves glycemic control and restores islet cell mass and function in a rodent model of type 2 diabetes
21. Role of central serotonin and melanocortin systems in the control of energy balance • Review article
22. Epigenetic changes in the hypothalamic pro-opiomelanocortin gene: A mechanism linking maternal undernutrition to obesity in the offspring? • Review article
23. The soy isoflavone genistein reverses oxidative and inflammatory state, neuropathic pain, neurotrophic and vasculature deficits in diabetes mouse model
24. Vascular protection by dietary polyphenols • Review article

Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: A review of their intracellular targets • Review article